Detection and Time Course of Formation of Major Thiamin Diphosphate-Bound Covalent Intermediates Derived from a Chromophoric Substrate Analogue on Benzoylformate Decarboxylase

The mechanism of the enzyme benzoylformate decarboxylase (BFDC), which carries out a typical thiamin diphosphate (ThDP)-dependent nonoxidative decarboxylation reaction, was studied with the chromophoric alternate substrate (E)-2-oxo-4(pyridin-3-yl)-3-butenoic acid (3-PKB). Addition of 3-PKB resulted...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chakraborty, Sumit, Nemeria, Natalia S., Balakrishnan, Anand, Brandt, Gabriel S., Kneen, Malea M., Yep, Alejandra, McLeish, Michael J., Kenyon, George L., Petsko, Gregory A., Ringe, Dagmar, Jordan, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788921/
https://ncbi.nlm.nih.gov/pubmed/19140682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801810h
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados