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A Theoretical Study of the Benzoylformate Decarboxylase Reaction Mechanism

Density functional theory calculations are used to investigate the detailed reaction mechanism of benzoylformate decarboxylase, a thiamin diphosphate (ThDP)-dependent enzyme that catalyzes the nonoxidative decarboxylation of benzoylformate yielding benzaldehyde and carbon dioxide. A large model of t...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Planas, Ferran, Sheng, Xiang, McLeish, Michael J., Himo, Fahmi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028569/
https://ncbi.nlm.nih.gov/pubmed/29998094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00205
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