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The Reaction Mechanism of Phenylethanolamine N-Methyltransferase: A Density Functional Theory Study
Hybrid density functional theory methods were used to investigate the reaction mechanism of human phenylethanolamine N-methyltransferase (hPNMT). This enzyme catalyzes the S-adenosyl-l-methionine-dependent conversion of norepinephrine to epinephrine, which constitutes the terminal step in the catech...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760686/ https://ncbi.nlm.nih.gov/pubmed/19733262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2009.08.022 |
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