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Interferon-resistant Daudi Cell Line with a Stat2 Defect Is Resistant to Apoptosis Induced by Chemotherapeutic Agents

Interferon-α (IFNα) has shown promise in the treatment of various cancers. However, the development of IFN resistance is a significant drawback. Using conditions that mimic in vivo selection of IFN-resistant cells, the RST2 IFN-resistant cell line was isolated from the highly IFN-sensitive Daudi hum...

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Detalhes bibliográficos
Main Authors: Du, Ziyun, Fan, Meiyun, Kim, Jong-Gwan, Eckerle, Dara, Lothstein, Leonard, Wei, Lai, Pfeffer, Lawrence M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788831/
https://ncbi.nlm.nih.gov/pubmed/19687011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.028324
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