Φορτώνει......
Biochemical Basis of Immunological and Retroviral Responses to DNA-targeted Cytosine Deamination by Activation-induced Cytidine Deaminase and APOBEC3G
Activation-induced cytidine deaminase (AID) and APOBEC3G catalyze deamination of cytosine to uracil on single-stranded DNA, thereby setting in motion a regulated hypermutagenic process essential for human well-being. However, if regulation fails, havoc ensues. AID plays a central role in the synthes...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
American Society for Biochemistry and Molecular Biology
2009
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788826/ https://ncbi.nlm.nih.gov/pubmed/19684020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R109.052449 |
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