Stochastic properties of processive cytidine DNA deaminases AID and APOBEC3G

Activation-induced (cytidine) deaminase (AID) efficiently introduces multiple and diversified deaminations in immunoglobulin (Ig) variable and switch regions. Here, we review studies of AID, and the APOBEC family member, APOBEC3G, demonstrating that both enzymes introduce multiple deaminations by pr...

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Bibliografische gegevens
Hoofdauteurs: Chelico, Linda, Pham, Phuong, Goodman, Myron F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Royal Society 2008
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660917/
https://ncbi.nlm.nih.gov/pubmed/19022738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0195
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