Stochastic properties of processive cytidine DNA deaminases AID and APOBEC3G

Activation-induced (cytidine) deaminase (AID) efficiently introduces multiple and diversified deaminations in immunoglobulin (Ig) variable and switch regions. Here, we review studies of AID, and the APOBEC family member, APOBEC3G, demonstrating that both enzymes introduce multiple deaminations by pr...

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Autors principals: Chelico, Linda, Pham, Phuong, Goodman, Myron F.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660917/
https://ncbi.nlm.nih.gov/pubmed/19022738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0195
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