Stochastic properties of processive cytidine DNA deaminases AID and APOBEC3G

Activation-induced (cytidine) deaminase (AID) efficiently introduces multiple and diversified deaminations in immunoglobulin (Ig) variable and switch regions. Here, we review studies of AID, and the APOBEC family member, APOBEC3G, demonstrating that both enzymes introduce multiple deaminations by pr...

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Main Authors: Chelico, Linda, Pham, Phuong, Goodman, Myron F.
Formato: Artigo
Idioma:Inglês
Publicado: The Royal Society 2008
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660917/
https://ncbi.nlm.nih.gov/pubmed/19022738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0195
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