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Identification of O-glycosylated decapeptides within the MUC1 repeat domain as potential MHC class I (A2) binding epitopes
The MUC1 glycoprotein is considered a tumor antigen due to its over-expression and aberrant glycosylation in cancer tissues. The latter results in appearance of new antigenic tumor-specific glycopeptides not found on normal glycoforms of the mucin. MUC1 glycopeptides can be presented by APCs on MHC...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788793/ https://ncbi.nlm.nih.gov/pubmed/19007994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.09.032 |
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