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Complex Carbohydrates Are Not Removed During Processing of Glycoproteins by Dendritic Cells: Processing of Tumor Antigen MUC1 Glycopeptides for Presentation to Major Histocompatibility Complex Class II–restricted T Cells

In contrast to protein antigens, processing of glycoproteins by dendritic cells (DCs) for presentation to T cells has not been well studied. We developed mouse T cell hybridomas to study processing and presentation of the tumor antigen MUC1 as a model glycoprotein. MUC1 is expressed on the surface a...

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Detalhes bibliográficos
Main Authors: Vlad, Anda M., Muller, Stefan, Cudic, Mare, Paulsen, Hans, Otvos, Laszlo, Hanisch, Franz-Georg, Finn, Olivera J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194269/
https://ncbi.nlm.nih.gov/pubmed/12461079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020493
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