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Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms

MUC1 is a transmembrane mucin with important functions in normal and transformed cells, carried out by the extracellular domain or the cytoplasmic tail. A characteristic feature of the MUC1 extracellular domain is the variable number of tandem repeats (VNTR) region. Alternative splicing may regulate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Lixin, Vlad, Anda, Milcarek, Christine, Finn, Olivera J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538090/
https://ncbi.nlm.nih.gov/pubmed/22941036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-012-1325-2
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