PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation

Loss of Cdc2 activity following Cyclin B degradation is necessary, but not sufficient, for mitotic exit. Proteins phosphorylated by Cdc2 and downstream mitotic kinases must also be dephosphorylated. We report here that protein phosphatase-1 (PP1) is the major catalyst of mitotic phosphoprotein depho...

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Bibliografiske detaljer
Main Authors: Wu, Judy Qiju, Guo, Jessie Yanxiang, Tang, Wanli, Yang, Chih-Sheng, Freel, Christopher D., Chen, Chen, Nairn, Angus C., Kornbluth, Sally
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788612/
https://ncbi.nlm.nih.gov/pubmed/19396163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1871
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