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Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway
Selective degeneration of midbrain dopaminergic (mDA) neurons is associated with Parkinson’s disease (PD), and thus an in-depth understanding of molecular pathways underlying mDA development will be crucial for optimal bioassays and cell replacement therapy for PD. In this study, we identified a nov...
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主要な著者: | , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2009
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788512/ https://ncbi.nlm.nih.gov/pubmed/19951692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2009.09.015 |
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