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Foxa1 and Foxa2 orchestrate development of the urethral tube and division of the embryonic cloaca through an autoregulatory loop with Shh

Congenital anomalies of external genitalia affect approximately 1 in 125 live male births. Development of the genital tubercle, the precursor of the penis and clitoris, is regulated by the urethral plate epithelium, an endodermal signaling center. Signaling activity of the urethral plate is mediated...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Gredler, Marissa L., Patterson, Sara E., Seifert, Ashley W., Cohn, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484041/
https://ncbi.nlm.nih.gov/pubmed/32645357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2020.06.009
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