KN-62 Analogues as Potent Differentiating Agents of HL-60 Cells

KN-62, an inhibitor of the calmodulin-dependent protein kinases (CaMKs), enhances the terminal differentiation of retinoic acid sensitive human myeloid leukemia cell lines. In an effort to identify additional CaMK inhibitors that exhibit more potent activity in triggering leukemia cell differentiati...

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Detalhes bibliográficos
Main Authors: Schuler, Aaron D., Si, Jutong, Mueller, LeMoyne, Simon, Julian A., Collins, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788433/
https://ncbi.nlm.nih.gov/pubmed/16963120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2006.07.022
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2788433/
https://ncbi.nlm.nih.gov/pubmed/16963120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2006.07.022