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The isoquinoline derivative KN-62 a potent antagonist of the P2Z-receptor of human lymphocytes
1. Extracellular adenosine 5′-triphosphate (ATP) is an agonist for a P2Z receptor on human lymphocytes which mediates opening of a cation-selective ion channel, activation of phospholipase D and shedding of the adhesion molecule, L-selectin, from the cell surface. The isoquinolinesulphonamides, KN-6...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564633/ https://ncbi.nlm.nih.gov/pubmed/9113369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701081 |
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