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Regulation of Lhb and Egr1 Gene Expression by GNRH Pulses in Rat Pituitaries Is Both c-Jun N-Terminal Kinase (JNK)- and Extracellular Signal-Regulated Kinase (ERK)-Dependent

Pulsatile GNRH regulates the gonadotropin subunit genes in a differential manner, with faster frequencies favoring Lhb gene expression and slower frequencies favoring Fshb. Early growth response 1 (EGR1) is critical for Lhb gene transcription. We examined GNRH regulation of EGR1 and its two corepres...

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Detalhes bibliográficos
Main Authors: Burger, Laura L., Haisenleder, Daniel J., Aylor, Kevin W., Marshall, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788048/
https://ncbi.nlm.nih.gov/pubmed/19710510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.079426
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