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Regulation of Intracellular Signaling Cascades by GNRH Pulse Frequency in the Rat Pituitary: Roles for CaMK II, ERK, and JNK Activation

Pulsatile GnRH (GNRH) differentially regulates LH and FSH subunit genes, with faster frequencies favoring Lhb transcription and slower favoring Fshb. Various intracellular pathways mediate the effects of GNRH, including CaMK II (CAMK2), ERK, and JNK. We examined whether activation of these pathways...

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Detalhes bibliográficos
Main Authors: Burger, Laura L., Haisenleder, Daniel J., Aylor, Kevin W., Marshall, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574636/
https://ncbi.nlm.nih.gov/pubmed/18716286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.070987
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