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Increased Expression of Glutathione Peroxidase 4 Strongly Protects Retina from Oxidative Damage

Oxidative damage contributes to cone cell death in retinitis pigmentosa and death of rods, cones, and retinal pigmented epithelial (RPE) cells in age-related macular degeneration. In this study, we explored the strategy of overexpressing components of the endogenous antioxidant defense system to com...

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Detalhes bibliográficos
Main Authors: Lu, Lili, Oveson, Brain C., Jo, Young–Joon, Lauer, Thomas W., Usui, Shinichi, Komeima, Keiichi, Xie, Bing, Campochiaro, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787833/
https://ncbi.nlm.nih.gov/pubmed/18823256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2008.2171
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