Increased Expression of Catalase and Superoxide Dismutase 2 Reduces Cone Cell Death in Retinitis Pigmentosa

Oxidative and nitrosative damage are major contributors to cone cell death in retinitis pigmentosa (RP). In this study, we explored the effects of augmenting components of the endogenous antioxidant defense system in models of RP, rd1, and rd10 mice. Unexpectedly, overexpression of superoxide dismut...

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Detalhes bibliográficos
Main Authors: Usui, Shinichi, Komeima, Keiichi, Lee, Sun Young, Jo, Young-Joon, Ueno, Shinji, Rogers, Brian S, Wu, Zhihao, Shen, Jikui, Lu, Lili, Oveson, Brian C, Rabinovitch, Peter S, Campochiaro, Peter A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803613/
https://ncbi.nlm.nih.gov/pubmed/19293779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.47
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