Increased Expression of Catalase and Superoxide Dismutase 2 Reduces Cone Cell Death in Retinitis Pigmentosa

Oxidative and nitrosative damage are major contributors to cone cell death in retinitis pigmentosa (RP). In this study, we explored the effects of augmenting components of the endogenous antioxidant defense system in models of RP, rd1, and rd10 mice. Unexpectedly, overexpression of superoxide dismut...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Usui, Shinichi, Komeima, Keiichi, Lee, Sun Young, Jo, Young-Joon, Ueno, Shinji, Rogers, Brian S, Wu, Zhihao, Shen, Jikui, Lu, Lili, Oveson, Brian C, Rabinovitch, Peter S, Campochiaro, Peter A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2009
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803613/
https://ncbi.nlm.nih.gov/pubmed/19293779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.47
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