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Role of Glutathione Peroxidase 4 in Glutamate-Induced Oxytosis in the Retina

PURPOSE: The purpose of the present study was to investigate the role of glutathione peroxidase 4 (GPx4) in glutamate-induced oxytosis in the retina. METHODS: For in vitro studies, an immortalized rat retinal precursor cell line R28 was used. Cells were transfected with siRNA specifically silencing...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sakai, Osamu, Uchida, Takatoshi, Roggia, Murilo F., Imai, Hirotaka, Ueta, Takashi, Amano, Shiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470664/
https://ncbi.nlm.nih.gov/pubmed/26083388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130467
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