Llwytho...

Controlling Subcellular Localization to Alter Function: Sending Oncogenic Bcr-Abl to the Nucleus Causes Apoptosis

Altering the subcellular localization of signal transducing proteins is a novel approach for therapeutic intervention. Mislocalization of tumor suppressors, oncogenes, or factors involved in apoptosis result in aberrant functioning of these proteins, leading to disease. In the case of chronic myelog...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dixon, Andrew S., Kakar, Mudit, Schneider, Korbinian M.H., Constance, Jonathan E., Paullin, Blake C., Lim, Carol S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787801/
https://ncbi.nlm.nih.gov/pubmed/19576252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.06.026
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