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Mitochondrial haplotypes may modulate the phenotypic manifestation of the deafness-associated 12S rRNA 1555A>G mutation
Mitochondrial 12S rRNA 1555A>G mutation is one of the important causes of aminoglycoside-induced and nonsyndromic deafness. Our previous investigations showed that the A1555G mutation was a primary factor underlying the development of deafness but was insufficient to produce deafness phenotype. H...
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Главные авторы: | , , , , , , , , , , , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
2009
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Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787746/ https://ncbi.nlm.nih.gov/pubmed/19818876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2009.09.007 |
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