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Dynamics: the missing link between structure and function of the viral RNA-dependent RNA polymerase?
The structural basis for nucleotide incorporation fidelity remains an open question for all nucleic acid polymerases. Addressing this question for the viral RNA-dependent RNA polymerase (RdRp) is of particular, practical significance because it is a determinant of sensitivity to antiviral nucleoside...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier Ltd.
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787719/ https://ncbi.nlm.nih.gov/pubmed/19910183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2009.10.012 |
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