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Cell-Autonomous Generation of Mitochondrial Superoxide is a Signal for Cell Death in Differentiated Neuronal Precursor Cells

The vast majority of optic neuropathies result from retinal ganglion cell (RGC) axonal injury. This induces cell death and is associated with a burst of mitochondria-generated superoxide within the soma. It is unclear whether there is a clear causal relationship between superoxide generation and cel...

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Detalhes bibliográficos
Main Authors: Scott, Colin J., Seidler, Emily A., Levin, Leonard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787709/
https://ncbi.nlm.nih.gov/pubmed/19819231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.10.004
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