FAS Promoter Polymorphism: Outcome of Childhood Acute Myeloid Leukemia. A Children’s Oncology Group Report

PURPOSE: FAS is a cell surface receptor involved in apoptotic signal transmission. Deregulation of this pathway results in down regulation of apoptosis and subsequent persistence of a malignant clone. A single nucleotide polymorphism resulting in guanine-to-adenine (G→A) transition in the FAS promot...

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Главные авторы: Mehta, Parinda A, Gerbing, Robert B, Alonzo, Todd A, Elliott, James S, Zamzow, Tiffany A, Combs, Michelle, Stover, Emily, Ross, Julie A, Perentesis, John P, Meschinchi, Soheil, Lange, Beverly J, Davies, Stella M
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787450/
https://ncbi.nlm.nih.gov/pubmed/19047119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0418
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