FAS Promoter Polymorphism: Outcome of Childhood Acute Myeloid Leukemia. A Children’s Oncology Group Report

PURPOSE: FAS is a cell surface receptor involved in apoptotic signal transmission. Deregulation of this pathway results in down regulation of apoptosis and subsequent persistence of a malignant clone. A single nucleotide polymorphism resulting in guanine-to-adenine (G→A) transition in the FAS promot...

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Main Authors: Mehta, Parinda A, Gerbing, Robert B, Alonzo, Todd A, Elliott, James S, Zamzow, Tiffany A, Combs, Michelle, Stover, Emily, Ross, Julie A, Perentesis, John P, Meschinchi, Soheil, Lange, Beverly J, Davies, Stella M
格式: Artigo
語言:Inglês
出版: 2008
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787450/
https://ncbi.nlm.nih.gov/pubmed/19047119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0418
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