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Multiple Binding Modes between HNF4α and the LXXLL Motifs of PGC-1α Lead to Full Activation

Hepatocyte nuclear factor 4α (HNF4α) is a novel nuclear receptor that participates in a hierarchical network of transcription factors regulating the development and physiology of such vital organs as the liver, pancreas, and kidney. Among the various transcriptional coregulators with which HNF4α int...

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Autores principales: Rha, Geun Bae, Wu, Guangteng, Shoelson, Steven E., Chi, Young-In
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787377/
https://ncbi.nlm.nih.gov/pubmed/19846556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.052506
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