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Mechanical Loading Regulates NFATc1 and β-Catenin Signaling through a GSK3β Control Node

Mechanical stimulation can prevent adipogenic and improve osteogenic lineage allocation of mesenchymal stem cells (MSC), an effect associated with the preservation of β-catenin levels. We asked whether mechanical up-regulation of β-catenin was critical to reduction in adipogenesis as well as other m...

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Detalhes bibliográficos
Main Authors: Sen, Buer, Styner, Maya, Xie, Zhihui, Case, Natasha, Rubin, Clinton T., Rubin, Janet
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787323/
https://ncbi.nlm.nih.gov/pubmed/19840939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.039453
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