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β-Catenin Levels Influence Rapid Mechanical Responses in Osteoblasts

Mechanical loading of bone initiates an anabolic, anticatabolic pattern of response, yet the molecular events involved in mechanical signal transduction are not well understood. Wnt/β-catenin signaling has been recognized in promoting bone anabolism, and application of strain has been shown to induc...

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Detalhes bibliográficos
Main Authors: Case, Natasha, Ma, Meiyun, Sen, Buer, Xie, Zhihui, Gross, Ted S., Rubin, Janet
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570859/
https://ncbi.nlm.nih.gov/pubmed/18723514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801907200
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