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Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells

INTRODUCTION: Loss of intervertebral disc (IVD) matrix and ultimately disc height as a result of 'degeneration' has been implicated as a major cause of low back pain (LBP). The use of anabolic growth factors as therapies to regenerate IVD matrix, hence restoring disc height and thus revers...

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Detalhes bibliográficos
Main Authors: Le Maitre, Christine L, Freemont, Anthony J, Hoyland, Judith A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787300/
https://ncbi.nlm.nih.gov/pubmed/19754961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2808
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