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Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1

The ability of carcinoma cells arising at primary sites to cross their underlying basement membrane (BM), a specialized form of extracellular matrix that subtends all epithelial cells, and to access the host vasculature are central features of the malignant phenotype. The initiation of the invasive...

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Autors principals: Ota, Ichiro, Li, Xiao-Yan, Hu, Yuexian, Weiss, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787166/
https://ncbi.nlm.nih.gov/pubmed/19915148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910962106
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