MST1-dependent vesicle trafficking regulates neutrophil transmigration through the vascular basement membrane

Neutrophils need to penetrate the perivascular basement membrane for successful extravasation into inflamed tissue, but this process is incompletely understood. Recent findings have associated mammalian sterile 20–like kinase 1 (MST1) loss of function with a human primary immunodeficiency disorder,...

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Publicado en:J Clin Invest
Autores principales: Kurz, Angela R.M., Pruenster, Monika, Rohwedder, Ina, Ramadass, Mahalakshmi, Schäfer, Kerstin, Harrison, Ute, Gouveia, Gabriel, Nussbaum, Claudia, Immler, Roland, Wiessner, Johannes R., Margraf, Andreas, Lim, Dae-Sik, Walzog, Barbara, Dietzel, Steffen, Moser, Markus, Klein, Christoph, Vestweber, Dietmar, Haas, Rainer, Catz, Sergio D., Sperandio, Markus
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096904/
https://ncbi.nlm.nih.gov/pubmed/27701149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87043
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