Extracellular MRP8/14 is a regulator of β2 integrin-dependent neutrophil slow rolling and adhesion

Myeloid-related proteins (MRPs) 8 and 14 are cytosolic proteins secreted from myeloid cells as proinflammatory mediators. Currently, the functional role of circulating extracellular MRP8/14 is unclear. Our present study identifies extracellular MRP8/14 as an autocrine player in the leukocyte adhesio...

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Publicado no:Nat Commun
Main Authors: Pruenster, Monika, Kurz, Angela R. M., Chung, Kyoung-Jin, Cao-Ehlker, Xiao, Bieber, Stephanie, Nussbaum, Claudia F., Bierschenk, Susanne, Eggersmann, Tanja K., Rohwedder, Ina, Heinig, Kristina, Immler, Roland, Moser, Markus, Koedel, Uwe, Gran, Sandra, McEver, Rodger P., Vestweber, Dietmar, Verschoor, Admar, Leanderson, Tomas, Chavakis, Triantafyllos, Roth, Johannes, Vogl, Thomas, Sperandio, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411303/
https://ncbi.nlm.nih.gov/pubmed/25892652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7915
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