Extracellular MRP8/14 is a regulator of β2 integrin-dependent neutrophil slow rolling and adhesion

Myeloid-related proteins (MRPs) 8 and 14 are cytosolic proteins secreted from myeloid cells as proinflammatory mediators. Currently, the functional role of circulating extracellular MRP8/14 is unclear. Our present study identifies extracellular MRP8/14 as an autocrine player in the leukocyte adhesio...

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Published in:Nat Commun
Main Authors: Pruenster, Monika, Kurz, Angela R. M., Chung, Kyoung-Jin, Cao-Ehlker, Xiao, Bieber, Stephanie, Nussbaum, Claudia F., Bierschenk, Susanne, Eggersmann, Tanja K., Rohwedder, Ina, Heinig, Kristina, Immler, Roland, Moser, Markus, Koedel, Uwe, Gran, Sandra, McEver, Rodger P., Vestweber, Dietmar, Verschoor, Admar, Leanderson, Tomas, Chavakis, Triantafyllos, Roth, Johannes, Vogl, Thomas, Sperandio, Markus
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411303/
https://ncbi.nlm.nih.gov/pubmed/25892652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7915
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