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A cancer cell metalloprotease triad regulates the basement membrane transmigration program

Carcinoma cells initiate the metastatic cascade by inserting invasive pseudopodia through breaches in the basement membrane (BM), a specialized barrier of cross-linked, extracellular matrix macromolecules that underlies epithelial cells and ensheaths blood vessels. While BM invasion is the sine qua...

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Detalles Bibliográficos
Autores principales: Hotary, Kevin, Li, Xiao-Yan, Allen, Edward, Stevens, Susan L., Weiss, Stephen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578694/
https://ncbi.nlm.nih.gov/pubmed/16983145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1451806
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