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A 5′ cytosine binding pocket in Puf3p specifies regulation of mitochondrial mRNAs

A single regulatory protein can control the fate of many mRNAs with related functions. The Puf3 protein of Saccharomyces cerevisiae is exemplary, as it binds and regulates more than 100 mRNAs that encode proteins with mitochondrial function. Here we elucidate the structural basis of that specificity...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhu, Deyu, Stumpf, Craig R., Krahn, Joseph M., Wickens, Marvin, Hall, Traci M. Tanaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787145/
https://ncbi.nlm.nih.gov/pubmed/19918084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812079106
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