A 5′ cytosine binding pocket in Puf3p specifies regulation of mitochondrial mRNAs

A single regulatory protein can control the fate of many mRNAs with related functions. The Puf3 protein of Saccharomyces cerevisiae is exemplary, as it binds and regulates more than 100 mRNAs that encode proteins with mitochondrial function. Here we elucidate the structural basis of that specificity...

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Bibliografiske detaljer
Main Authors: Zhu, Deyu, Stumpf, Craig R., Krahn, Joseph M., Wickens, Marvin, Hall, Traci M. Tanaka
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787145/
https://ncbi.nlm.nih.gov/pubmed/19918084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812079106
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