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Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development
Dicer, a ribonuclease essential for miRNA processing, is expressed abundantly in developing mouse cornea and lens. We studied the roles of Dicer and miRNAs in eye development by conditionally deleting the Dicer gene in the mouse lens and corneal epithelium. Adult Dicer conditional null (DicerCN) mic...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787093/ https://ncbi.nlm.nih.gov/pubmed/19681134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22056 |
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