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Targeted Deletion of AP-2α Leads to Disruption in Corneal Epithelial Cell Integrity and Defects in the Corneal Stroma

PURPOSE: The present study was undertaken to create a conditional knockout of AP-2α in the corneal epithelium. METHODS: A line of mice expressing Cre-recombinase specifically in the early lens placode was crossed with mice in which the AP-2α allele is flanked by two loxP sites. The resultant Le-AP-2...

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Bibliografiska uppgifter
Huvudupphovsmän: Dwivedi, Dhruva J., Pontoriero, Giuseppe F., Ashery-Padan, Ruth, Sullivan, Shelley, Williams, Trevor, West-Mays, Judith A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2005
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517422/
https://ncbi.nlm.nih.gov/pubmed/16186342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.05-0028
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