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Cell Autonomous Roles for AP-2α in Lens Vesicle Separation and Maintenance of the Lens Epithelial Cell Phenotype
In this study, we have created a conditional deletion of AP-2α in the developing mouse lens (Le-AP-2α mutants) to determine the cell-autonomous requirement(s) for AP-2α in lens development. Embryonic and adult Le-AP-2α mutants exhibited defects confined to lens placode derivatives, including a persi...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517426/ https://ncbi.nlm.nih.gov/pubmed/18224708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21445 |
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