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Cell Autonomous Roles for AP-2α in Lens Vesicle Separation and Maintenance of the Lens Epithelial Cell Phenotype

In this study, we have created a conditional deletion of AP-2α in the developing mouse lens (Le-AP-2α mutants) to determine the cell-autonomous requirement(s) for AP-2α in lens development. Embryonic and adult Le-AP-2α mutants exhibited defects confined to lens placode derivatives, including a persi...

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書誌詳細
主要な著者: Pontoriero, Giuseppe F., Deschamps, Paula, Ashery-Padan, Ruth, Wong, Ryan, Yang, Ying, Zavadil, Jiri, Cvekl, Ales, Sullivan, Shelley, Williams, Trevor, West-Mays, Judith A.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517426/
https://ncbi.nlm.nih.gov/pubmed/18224708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21445
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