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AP-2β Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development

PURPOSE: The homeodomain transcription factor, PITX2, is at the apex of a genetic pathway required for corneal development, but the critical effector genes regulated by the PITX2 remain unknown. The purpose of this study was to discover and validate PITX2-dependent mechanisms required for specifying...

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Bibliographische Detailangaben
Veröffentlicht in:Invest Ophthalmol Vis Sci
Hauptverfasser: Chen, Lisheng, Martino, Vanessa, Dombkowski, Alan, Williams, Trevor, West-Mays, Judith, Gage, Philip J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4790471/
https://ncbi.nlm.nih.gov/pubmed/26968737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-18103
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