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Heterozygous Pitx2 Null Mice Accurately Recapitulate the Ocular Features of Axenfeld-Rieger Syndrome and Congenital Glaucoma

PURPOSE: The purpose of this analysis was to assess the utility of Pitx2(+/−) mice as a model for the ocular features of Axenfeld-Rieger Syndrome and for congenital glaucoma. METHODS: Eyes of Pitx2(+/−) and wild-type littermates were examined clinically using optical coherence tomography (OCT) and f...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Chen, Lisheng, Gage, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040192/
https://ncbi.nlm.nih.gov/pubmed/27654429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19700
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