PI3 Kinase signals BCR dependent mature B cell survival

Previous work has shown that mature B cells depend upon survival signals delivered to the cells by their antigen receptor (BCR). To identify the molecular nature of this survival signal, we have developed a genetic approach in which ablation of the BCR is combined with the activation of specific, BC...

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Bibliographische Detailangaben
Hauptverfasser: Srinivasan, Lakshmi, Sasaki, Yoshiteru, Calado, Dinis Pedro, Zhang, Baochun, Paik, Ji Hye, DePinho, Ronald A., Kutok, Jeffrey L., Kearney, John F., Otipoby, Kevin L., Rajewsky, Klaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787092/
https://ncbi.nlm.nih.gov/pubmed/19879843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.08.041
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