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Analysis of the plasticity of location of the Arg244 positive charge within the active site of the TEM-1 β-lactamase

A large number of β-lactamases have emerged that are capable of conferring bacterial resistance to β-lactam antibiotics. Comparison of the structural and functional features of this family has refined understanding of the catalytic properties of these enzymes. An arginine residue present at position...

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Bibliographic Details
Main Authors: Marciano, David C, Brown, Nicholas G, Palzkill, Timothy
Format: Artigo
Language:Inglês
Published: Wiley Subscription Services, Inc., A Wiley Company 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786972/
https://ncbi.nlm.nih.gov/pubmed/19672877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.220
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