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Proligands with protease-regulated binding activity identified from cell-displayed prodomain libraries
A general method was developed for the discovery of protease-activated binding ligands, or proligands, from combinatorial prodomain libraries displayed on the surface of E. coli. Peptide libraries of candidate prodomains were fused with a matrix metalloprotease-2 substrate linker to a vascular endot...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2786969/ https://ncbi.nlm.nih.gov/pubmed/19653300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.217 |
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