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Alternative Splicing Modulates Autoinhibition and SH3 Accessibility in the Src Kinase Fyn
Src family kinases are central regulators of a large number of signaling pathways. To adapt to the idiosyncrasies of different cell types, these kinases may need a fine-tuning of their intrinsic molecular control mechanisms. Here, we describe on a molecular level how the Fyn kinase uses alternative...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology (ASM)
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2786882/ https://ncbi.nlm.nih.gov/pubmed/19805512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00398-09 |
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