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Identification of Src, Fyn, Lyn, PI3K and Abl SH3 domain ligands using phage display libraries.

Many proteins involved in intracellular signal transduction contain a small, 50-60 amino acid domain, termed the Src homology 3 (SH3) domain. This domain appears to mediate critical protein-protein interactions that are involved in responses to extracellular signals. Previous studies have shown that...

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Bibliographic Details
Main Authors: Rickles, R J, Botfield, M C, Weng, Z, Taylor, J A, Green, O M, Brugge, J S, Zoller, M J
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC395523/
https://ncbi.nlm.nih.gov/pubmed/7988556
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