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Conversion of VPg into VPgpUpU(OH) before and during Poliovirus Negative-Strand RNA Synthesis
There are two protein primers involved in picornavirus RNA replication, VPg, the viral protein of the genome, and VPgpUpU(OH). A cis-acting replication element (CRE) within the open reading frame of poliovirus (PV) RNA allows the viral RNA-dependent RNA polymerase 3D(Pol) to catalyze the conversion...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2786823/ https://ncbi.nlm.nih.gov/pubmed/19812161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01676-08 |
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