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Pivotal role for glycogen synthase kinase–3 in hematopoietic stem cell homeostasis in mice
Hematopoietic stem cell (HSC) homeostasis depends on the balance between self renewal and lineage commitment, but what regulates this decision is not well understood. Using loss-of-function approaches in mice, we found that glycogen synthase kinase–3 (Gsk3) plays a pivotal role in controlling the de...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2786808/ https://ncbi.nlm.nih.gov/pubmed/19959876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40572 |
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