Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice

The respiratory tract is continuously exposed to both innocuous airborne antigens and immunostimulatory molecules of microbial origin, such as LPS. At low concentrations, airborne LPS can induce a lung DC–driven Th2 cell response to harmless inhaled antigens, thereby promoting allergic asthma. Howev...

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Auteurs principaux: Bedoret, Denis, Wallemacq, Hugues, Marichal, Thomas, Desmet, Christophe, Quesada Calvo, Florence, Henry, Emmanuelle, Closset, Rodrigue, Dewals, Benjamin, Thielen, Caroline, Gustin, Pascal, de Leval, Laurence, Van Rooijen, Nico, Le Moine, Alain, Vanderplasschen, Alain, Cataldo, Didier, Drion, Pierre-Vincent, Moser, Muriel, Lekeux, Pierre, Bureau, Fabrice
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786798/
https://ncbi.nlm.nih.gov/pubmed/19907079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39717
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