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Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice
The respiratory tract is continuously exposed to both innocuous airborne antigens and immunostimulatory molecules of microbial origin, such as LPS. At low concentrations, airborne LPS can induce a lung DC–driven Th2 cell response to harmless inhaled antigens, thereby promoting allergic asthma. Howev...
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2786798/ https://ncbi.nlm.nih.gov/pubmed/19907079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39717 |
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