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Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice
Membrane-bound proteases have recently emerged as critical mediators of tumorigenesis, angiogenesis, and metastasis. However, the mechanisms by which they regulate these processes remain unknown. As the cell surface serine protease fibroblast activation protein (FAP) is selectively expressed on tumo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2786791/ https://ncbi.nlm.nih.gov/pubmed/19920354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38988 |
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