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Gekko-sulfated Glycopeptide Inhibits Tumor Angiogenesis by Targeting Basic Fibroblast Growth Factor

Basic fibroblast growth factor (bFGF) is a therapeutic target of anti-angiogenesis. Here, we report that a novel sulfated glycopeptide derived from Gekko swinhonis Guenther (GSPP), an anticancer drug in traditional Chinese medicine, inhibits tumor angiogenesis by targeting bFGF. GSPP significantly d...

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Detalhes bibliográficos
Main Authors: Zhang, Shuang-Xia, Zhu, Cong, Ba, Yi, Chen, Dan, Zhou, Xing-Long, Cao, Rui, Wang, Li-Ping, Ren, Yuan, Wu, Xiong-Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340002/
https://ncbi.nlm.nih.gov/pubmed/22371501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.321521
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