ADS-J1 Inhibits Human Immunodeficiency Virus Type 1 Entry by Interacting with the gp41 Pocket Region and Blocking Fusion-Active gp41 Core Formation

We previously identified a small-molecule anti-human immunodeficiency virus type 1 (anti-HIV-1) compound, ADS-J1, using a computer-aided molecular docking technique for primary screening and a sandwich enzyme-linked immunosorbent assay (ELISA) as a secondary screening method. In the present study, w...

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Detalhes bibliográficos
Main Authors: Wang, Hongtao, Qi, Zhi, Guo, Angi, Mao, Qinchao, Lu, Hong, An, Xiuli, Xia, Chenglai, Li, Xiaojuan, Debnath, Asim K., Wu, Shuguang, Liu, Shuwen, Jiang, Shibo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786362/
https://ncbi.nlm.nih.gov/pubmed/19786602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00670-09
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